The island of Gozo constitutes the north-west of the Maltese archipelago. It is separated to the south-east of Malta's island, with between them the island of Comino and its brother islet, Cominotto. The Island of Gozo is separated from the Island of Comino by the 2,300-meter-wide Strait of Gozo and the 2,600-meter-wide Strait of Malta between the Island of Comino and the Island of Malta.
To the north is Sicily, from which it is separated by the Malta Canal, which is about 90 kilometers wide.